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doi:10.1038/s41598-024-65310-y Neelakantan H, Hommel JD, Watowich SJ, et al

The absorption rate varies, but improvements in symptoms can often be observed within a week or two of starting supplementation

Many patients experience reduced appetite and fluid intake when starting GLP-1 therapy, whilst the medicine's gastrointestinal effects including nausea and occasional vomiting can further affect hydration status